Computer Science and Artificial Intelligence Laboratory (CSAIL)

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  • Manolis Kellis, an associate professor of computer science at MIT and an associate member of the Broad Institute, is one of the lead computational scientists and authors of a paper that describes the functionality of the non-gene regions (about 80 percent) of the human genome, the so-called 'junk DNA'.
  • We study several natural problems in which an {\em unknown} distribution over an {\em unknown} population of vectors needs to be recovered from partial or noisy samples. Such problems naturally arise in a variety of contexts in learning, clustering, statistics, data mining and database privacy, where loss and error may be introduced by nature, inaccurate measurements, or on purpose.
  • Applying random linear projections, a.k.a. "sketching", has become a standard technique when analyzing high-dimensional data sets. The resulting algorithms are embarrassingly parallelizable and suitable for stream processing.
  • In his seminal paper, Myerson [1981] provides a revenue-optimal auction for a seller who is looking to sell a single item to multiple bidders. Extending this auction to simultaneously selling multiple heterogeneous items has been one of the central problems in Mathematical Economics. We provide such an extension that is also computationally efficient.
  • We solve a 20-year old problem posed by Yannakakis and prove that there exists no polynomial-size linear program (LP) whose associated polytope projects to the traveling salesman polytope, even if the LP is not required to be symmetric.

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