EECS Special Seminar: Ashwin Gopinath "DNA Origami: The Bridge to the Bottom"


Event Speaker: 

Ashwin Gopinath

Event Location: 

34-401 Grier A

Event Date/Time: 

Tuesday, February 20, 2018 - 3:00pm

Abstract: Conventional top-down nanofabrication, over the last six decades, has enabled almost all the complex electronic, optical and micro-fluidic devices that form the foundation of our society. Parallel efforts, exploring bottom-up self-assembly processes, have also enabled design and synthesis of structures like quantum dots, carbon nanotubes and unique bio-molecules that possess technologically relevant proper- ties unachievable top-down. While both these approaches have independently matured, ongoing efforts to create “hybrid nanostructures” combining both strategies, has been fraught with technical challenges. The main roadblock is the absence of a scalable method to deterministically organize components built bottom-up within top-down nanofabricated structures.
In this talk, I will first introduce a directed self-assembly technique that utilizes DNA origami as a molecular adaptor to modularly position, and orient, bottom-up nano-components (like quantum dots, light emitters and proteins) within top-down nanofabricated devices. I will then present experimental results demonstrating the utility of the technique to achieved absolute, arbitrarily scalable, control over the integration of discrete emitters inside optical devices. Finally, I conclude by presenting my vision of how this molecular bridge can enable a wide range of highly transformative, and functional, devices with relevance to both solid-state as well as microbiology.
Bio: Ashwin Gopinath is a research scientist in the Department of Bioengineering at California Institute of Technology, Pasadena, USA. He obtained his PhD degree from Boston University and he works at the intersection of nanofabrication, optical physics and synthetic biology.  His research is focused on developing scalable techniques to organize single-molecules, quantum optics, tools for single molecule biophysics and nanoparticle therapeutics. 
Host: Tomas Palacios