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MIT Electrical Engineering and Computer Science
Spring 2001 Catalogue Supplement |
TR 9:30-11, Room 13-5101
Professor Katrin Kneipp, Room 6-008, 3-3378
Prereq.: any one or more of the following: 6.013, 6.014, 8.03, 8.05, 8.07, 5.61, 10.920 or 10.55
3-0-9
Does not count as an Engineering Concentration Subject
The course is open to Grad and upper level UGrad students of Physics, EECS, Chemistry, Chemical Engineering, and Biology and others as interested.
Prerequisites listed below are recommended but not required:
Any one or more of the following: 6.013, 6.014, 8.03, 8.05, 8.07, 5.61, 10.920 OR 10.55
The course will introduce and discuss contemporary research in ultrasensitive laser spectroscopy in small volumes focused on spectroscopy of single molecules, including individual large artificial molecules, nanoparticles, and nanostructures. Background will be developed for understanding modern laser spectroscopic methods, applied for spectroscopy of single molecules (one- and two-photon excited fluorescence, linear and nonlinear Raman spectroscopy methods).
Spectroscopy in small volumes (confocal microscopy, evanescent field spectroscopy, microcavities, near field spectroscopy).
Spectroscopy in the vicinity of metallic nanostructures (optical properties and local optical fields of metallic nanostructures). Surface-enhanced Raman spectroscopy (SERS) (physics behind the effect, potential of SERS as a tool for probing molecules on surfaces and for trace analysis, related linear and nonlinear surface-enhanced optical effects).
Single molecule fluorescence spectroscopy. Single molecule Raman spectroscopy based on surface-enhanced Raman scattering (single molecule spectra vs. "many-molecule" spectra, statistics of spectroscopic signals (Gaussian, Poisson), new information from single molecule spectra, experimental aspects of single molecule detection and spectroscopy, comparison of single molecule fluorescence and Raman detection).
Applications of single molecule spectroscopy in physics, nanotechnology, biology, chemistry, and in biomedical and environmental sciences.
Single Molecule Spectroscopy Course